The Rise of Salmon DNA Facials: Exploring (PN) Polynucleotide and (PDRN) Polydeoxyribonucleotide Treatments

A new trend in Calabasas has emerged that's catching the attention of beauty enthusiasts like Kim Kardashian and aesthetic world alike—Salmon DNA facials. This innovative treatment, also known as PN (Polynucleotide) and PDRN (Polydeoxyribonucleotide) treatment, is making waves for its ability to rejuvenate and repair the skin from the inside out. Let's dive into what makes this treatment so special, and why it's becoming a must-try in the skincare community.

What is Salmon DNA Facial?

Salmon DNA facials are an advanced skincare treatment that utilizes DNA extracts from salmon, known for their remarkable healing and regenerative properties. The treatment primarily involves microneedling or applying products enriched with PDRN or PN directly onto the skin. These substances are known to stimulate skin repair, improve elasticity, and provide deep hydration.

The Science Behind Rejuran PN and PDRN Treatments

Salmon DNA is the most similar to human DNA found in nature, which is why it works so well for skin rejuvenation at a cellular level. Salmon DNA has high amounts of hyaluronic acid as well as amino acids and vitamins and nutrients that are beneficial for our skin. 

PN (Polynucleotide) and PDRN (Polydeoxyribonucleotide) are the key components in these treatments, derived from salmon DNA. Here's how they work:

PN (Polynucleotide): 

PN is a biopolymer composed of long-chain nucleotides, which are the building blocks of DNA. They are extracted from Salmon testes.  When applied to the skin, PN works by promoting the repair of damaged skin cells and enhancing the skin's natural regenerative processes. It boosts collagen production, improves skin texture, and reduces the appearance of fine lines and wrinkles.

Rejuran Healer PN is a very popular brand in Asia and now available in the United states.  Rejuran has clinically been proven to increase skin thickness, enhance skin elasticity, minimize healing time after procedures including microneedling, microneedling with RF, and ablative skin treatments, to name a few. It is safe to use on all skin types and people who have fish allergies.

PDRN (Polydeoxyribonucleotide): 

PDRN, a type of PN, is a shorter-chain nucleotide that is also extracted from salmon sperm. It has been widely studied for its anti-inflammatory and tissue-repairing properties. PDRN helps to accelerate wound healing, stimulate cell growth, and improve skin elasticity. It’s particularly effective in treating scars, fine lines, and signs of aging.

Klardie is a popular brand in the realm of PDRN treatments. Known for its high-quality formulations, Klardie offers a range of products that harness the power of PDRN to deliver rejuvenating effects. Klardie treatments are designed to provide intensive hydration, improve skin tone, and promote overall skin health. By incorporating PDRN into its products, Klardie offers a potent solution for those seeking to revitalize their skin and achieve a youthful glow.

Rejuran Tone up booster is another popular skin boosting product that offers PDRN in addition to other active ingredients to reverse signs of aging, improve skin texture, and brighten up dull looking skin.  In addition to the PDRN, this skin booster also contains tranexamic acid, which is a depigmentation agent to help combat pigmentation and melasma. 

kim kardashian and a salmon

The Benefits of Salmon DNA Facials

The popularity of Salmon DNA facials can be attributed to the numerous benefits they offer.


Enhanced Skin Repair: The PN and PDRN in these treatments promote cellular regeneration, helping to repair damaged skin and improve its overall health.

Anti-Aging Effects: By boosting collagen production and improving skin elasticity, Salmon DNA facials help to reduce the appearance of fine lines, wrinkles, and other signs of aging.

Deep Hydration: These treatments provide intense hydration to the skin, leaving it plump, smooth, and radiant.

Improved Skin Texture: Regular sessions can lead to a more refined skin texture, with reduced pores and a smoother surface.

Safe and Natural: Since PN and PDRN are naturally occurring substances, these treatments are generally safe and well-tolerated by most skin types.

What to Expect from a Salmon DNA Facial

A typical Salmon DNA facial involves a series of microneedling, microinjections, or topical applications of the Rejuran PN or PDRN products into the skin. The procedure is minimally invasive and usually takes about 30 to 60 minutes. Some redness and slight swelling may occur immediately after the treatment, but these effects typically subside within a few hours.

Most people notice an improvement in their skin's appearance after just one session, with optimal results seen after a series of treatments. The effects of Salmon DNA facials can last several months, making it a worthwhile investment for those looking to enhance their skin's vitality.

Salmon DNA facials represent a significant advancement in skincare. These treatments offer a natural and effective way to rejuvenate the skin, making them a popular choice for those seeking to combat the signs of aging and achieve a radiant complexion. Whether you're dealing with fine lines, scars, or just want to boost your skin's overall health, our founder Erin Gordon, M.D. can help you! Simply contact us through our website today to achieve healthy skin.

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